A Case of Cutaneous Dirt-Adherent-Like Sweet Syndrome in Pregnancy

Pregnancy-associated Sweet syndrome (PASS), is a diagnostically challenging entity, especially in atypical presentations. Delayed management may result in significant maternal-fetal risks. We describe a 24-year-old woman with PASS presenting like cutaneous dirt-adherent disease, characterized by abrupt-onset facial erythematous plaques with adherent dirt-like crusts. Histopathology revealed superficial dermal edema and dense perivascular neutrophilic infiltrates without vasculitis. Low-dose systemic corticosteroids (prednisone 20mg/day) achieved rapid resolution, underscoring their efficacy and safety in pregnancy. This case explores the potential pathogenesis of PASS and underscores the necessity for awareness among clinicians about PASS, contributing valuable insights into the diagnosis and management of this rare condition in pregnancy.

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Publication Details

Journal
International Journal of Women s Health
Published
2025-12-01
DOI
https://doi.org/10.2147/ijwh.s562354
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
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article

A Case of Cutaneous Dirt-Adherent-Like Sweet Syndrome in Pregnancy

Zhenqiang Ruan, Po‐An Tu, Debao Yu, Luan Yang
International Journal of Women s Health
Autoimmune and Inflammatory Disorders
article

A Case of Cutaneous Dirt-Adherent-Like Sweet Syndrome in Pregnancy

Zhenqiang Ruan, Po‐An Tu, Debao Yu, Luan Yang
article en

Abstract

Pregnancy-associated Sweet syndrome (PASS), is a diagnostically challenging entity, especially in atypical presentations. Delayed management may result in significant maternal-fetal risks. We describe a 24-year-old woman with PASS presenting like cutaneous dirt-adherent disease, characterized by abrupt-onset facial erythematous plaques with adherent dirt-like crusts. Histopathology revealed superficial dermal edema and dense perivascular neutrophilic infiltrates without vasculitis. Low-dose systemic corticosteroids (prednisone 20mg/day) achieved rapid resolution, underscoring their efficacy and safety in pregnancy. This case explores the potential pathogenesis of PASS and underscores the necessity for awareness among clinicians about PASS, contributing valuable insights into the diagnosis and management of this rare condition in pregnancy.

International Journal of Women s HealthVol. Volume 17
Peking University (CN), Peking University First Hospital (CN), Jinan Infectious Disease Hospital (CN), Shandong Center for Disease Control and Prevention (CN)
Openalex Percentile: Top 49%
Autoimmune and Inflammatory Disorders
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A Case of Cutaneous Dirt-Adherent-Like Sweet Syndrome in Pregnancy — Zhenqiang Ruan, Po‐An Tu, et al. · International Journal of Women s Health (2025) | TGRS Research Map | TGRS