Circulating PD-1+ effector memory T cells predict anti-PD-1 efficacy in advanced gastric cancer
Our data identify a high pretreatment percentage of PD-1<sup>+</sup> cells in TEM as a potential predictive biomarker for response to PD-1 blockade.
Authors
- Lianru Zhang
- Kongcheng Wang
- Kai Xin (ORCID: https://orcid.org/0009-0007-3277-0180)
- Qing Liu (ORCID: https://orcid.org/0000-0002-0257-0694)
- Wenxiu Chen (ORCID: https://orcid.org/0000-0001-5673-1783)
- Baorui Liu (ORCID: https://orcid.org/0000-0003-4888-8144)
- Jie Shao (ORCID: https://orcid.org/0000-0003-4679-9105)
Institutions
- Nanjing Drum Tower Hospital (CN)
- Jiangsu Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fimmu.2025.1720724
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China