From Mimic to Diagnosis: Primary Lung Adenocarcinoma Presenting as Peripheral Airspace Opacities Mimicking Organizing Pneumonia

Lung adenocarcinoma may occasionally present with radiographic features resembling organizing pneumonia (OP), resulting in diagnostic uncertainty, delayed recognition, and the risk of inappropriate management. We present a case of a 77-year-old man with diabetes mellitus, hypertension, and ischemic heart disease who developed bilateral pulmonary infiltrates. Radiological findings initially suggested OP; however, histopathological examination revealed a moderately differentiated mucinous adenocarcinoma favoring a primary lung tumor. This case underscores a significant diagnostic pitfall and highlights the necessity of histological confirmation when encountering atypical radiologic features.

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Publication Details

Journal
Saudi Journal of Radiology
Published
2025-12-10
DOI
https://doi.org/10.55038/qrm6h705
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
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article

From Mimic to Diagnosis: Primary Lung Adenocarcinoma Presenting as Peripheral Airspace Opacities Mimicking Organizing Pneumonia

Mutaz Khairo, SAIMA HAFIZ, May Alsharif, I.S. Khallaf et al.
Saudi Journal of Radiology
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

From Mimic to Diagnosis: Primary Lung Adenocarcinoma Presenting as Peripheral Airspace Opacities Mimicking Organizing Pneumonia

Mutaz Khairo, SAIMA HAFIZ, May Alsharif, I.S. Khallaf, Hadeel Mashhour Al-Qurashi, Dania Felemban
article en

Abstract

Lung adenocarcinoma may occasionally present with radiographic features resembling organizing pneumonia (OP), resulting in diagnostic uncertainty, delayed recognition, and the risk of inappropriate management. We present a case of a 77-year-old man with diabetes mellitus, hypertension, and ischemic heart disease who developed bilateral pulmonary infiltrates. Radiological findings initially suggested OP; however, histopathological examination revealed a moderately differentiated mucinous adenocarcinoma favoring a primary lung tumor. This case underscores a significant diagnostic pitfall and highlights the necessity of histological confirmation when encountering atypical radiologic features.

Saudi Journal of RadiologyVol. 4(RSSA)
King Abdullah Medical City (SA)
Openalex Percentile: Top 42%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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