Asymptomatic Cryptococcal Antigenemia: A Multi-clinic Cross-Sectional Study on the Prevalence, Associated Factors and Predictors of Three-Month Outcomes Among Antiretroviral-Naïve and Antiretroviral-Experienced HIV Patients in Dar es Salaam, Tanzania

The overall prevalence of ACA across the three HIV clinics in Dar es Salaam was 4.8%, with lower prevalence observed among ART-experienced patients compared to ART-naïve individuals. CrAg positivity was a strong predictor of adverse outcomes at three months in both populations. These findings underscore the need for more robust, risk-based guidelines on screening and surveillance even among ART-experienced patients.