Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability
Through systematic screening and optimization, we established a robust animal model of dengue virus infection via intraperitoneal injection in IFNAR-/- BALB/c mice. This model offers a valuable tool for future dengue research.
Authors
- Wenjiang Zheng (ORCID: https://orcid.org/0000-0001-5234-0339)
- Haishan Long
- Geng Li (ORCID: https://orcid.org/0000-0002-2441-2427)
- Zhong Ming (ORCID: https://orcid.org/0000-0001-9310-3460)
- Ye Zhou (ORCID: https://orcid.org/0009-0004-1537-7748)
- Qiuhong Li
- Zhendong Guo (ORCID: https://orcid.org/0000-0001-8705-7744)
- Lijuan Qiu (ORCID: https://orcid.org/0000-0003-2548-4534)
- dongyi Liao (ORCID: https://orcid.org/0009-0006-7256-1044)
- Liangwen Yu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- Guangzhou Experimental Station (CN)
- Key Laboratory of Guangdong Province (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Zhongshan Hospital (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1002/ame2.70090
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangzhou University of Chinese Medicine
- Guangzhou University