Human macrophages release exosomes containing anti-inflammatory microRNAs after phagocytosis of Leishmania infantum
We show that <i>L. infantum</i> infection induces the release of exosomes containing miRNAs that are capable of modifying the host immune environment, possibly suppressing microbicidal pathways and favoring parasite survival.
Authors
- Mary E. Wilson (ORCID: https://orcid.org/0000-0001-8680-7275)
- Bayan Zhanbolat
- Yani Chen
- Cinthia L. Hudachek
Institutions
- University of Iowa (US)
- Veterans Health Administration (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fimmu.2025.1593829
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Roy J. and Lucille A. Carver College of Medicine, University of Iowa