Overlapping forms of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis: Insights from a European multicenter study
This study delineates the heterogeneity of EGPA/GPA overlap and underscores the need for personalized treatment approaches. Future prospective studies should explore targeted therapies, including rituximab and IL-5 blockade, in these overlapping AAV subtypes.
Authors
- Sergey Moiseev (ORCID: https://orcid.org/0000-0002-7232-4640)
- Jan Willem Cohen Tervaert (ORCID: https://orcid.org/0000-0001-7407-6364)
- Allyson Egan
- Nils Venhoff (ORCID: https://orcid.org/0000-0001-7729-2759)
- Vítor Teixeira (ORCID: https://orcid.org/0000-0002-9452-0028)
- Achille Aouba (ORCID: https://orcid.org/0000-0003-1726-3811)
- Roberto Padoan (ORCID: https://orcid.org/0000-0002-2356-375X)
- Pavel Novikov (ORCID: https://orcid.org/0000-0003-0148-5655)
- Michele Iudici (ORCID: https://orcid.org/0000-0001-5871-8806)
- Julien Campagne (ORCID: https://orcid.org/0000-0002-6186-4334)
- Franco Franceschini (ORCID: https://orcid.org/0000-0003-3678-6124)
- Gianluca Moroncini (ORCID: https://orcid.org/0000-0002-0380-0105)
- M. Ruivard
- Enrico Tombetti (ORCID: https://orcid.org/0000-0002-7122-9713)
- Diane Riehl
- Luca Quartuccio (ORCID: https://orcid.org/0000-0002-0134-6439)
- Alexis Régent (ORCID: https://orcid.org/0000-0002-8136-2454)
- Federico Alberici (ORCID: https://orcid.org/0000-0002-1686-5709)
- Samuel Deshayes (ORCID: https://orcid.org/0000-0001-8887-3233)
- Boris Sorin (ORCID: https://orcid.org/0000-0002-3443-9201)
- Silke R. Brix (ORCID: https://orcid.org/0000-0002-6002-6750)
- Xavier Puéchal (ORCID: https://orcid.org/0000-0003-3573-9203)
- Francesca Regola (ORCID: https://orcid.org/0000-0001-6560-1112)
- C. Mettler (ORCID: https://orcid.org/0000-0002-1649-3175)
- David R.W. Jayne (ORCID: https://orcid.org/0000-0002-1712-0637)
- Paul Legendre (ORCID: https://orcid.org/0000-0003-2787-5491)
- Martin Michaud (ORCID: https://orcid.org/0000-0003-1461-7733)
- Claudia Iannone (ORCID: https://orcid.org/0009-0005-5686-0127)
- Christian Pagnoux (ORCID: https://orcid.org/0000-0001-6287-9549)
- S. Rosenstingl
- Anne-Claire Billet (ORCID: https://orcid.org/0000-0003-3677-0739)
- Luisa Brussino (ORCID: https://orcid.org/0000-0001-7249-7616)
- Matthias Papo (ORCID: https://orcid.org/0000-0003-3389-9473)
- Paolo Delvino (ORCID: https://orcid.org/0000-0002-6383-8236)
- Loı̈c Guillevin (ORCID: https://orcid.org/0000-0001-6463-2160)
- Clara Jaccard
- Marco Caminati (ORCID: https://orcid.org/0009-0009-1134-059X)
- Mario Andrea Piga (ORCID: https://orcid.org/0000-0001-8678-1650)
- Paola Parronchi
- Benjamin Terrier (ORCID: https://orcid.org/0000-0001-6612-7336)
- Federica Pallotti (ORCID: https://orcid.org/0009-0009-7986-9190)
- Abdul‐Hadi Kafagi (ORCID: https://orcid.org/0000-0003-1214-3204)
- Vincent Cottin
- Marin Moutel
- Jean‐Marc Galempoix
Institutions
- University of Verona (IT)
- Marche Polytechnic University (IT)
- University of Udine (IT)
- Mount Sinai Hospital (CA)
- University of Padua (IT)
- University of Alberta (CA)
- Sechenov University (RU)
- University of Cambridge (GB)
- University Medical Center Freiburg (DE)
- Tallaght University Hospital (IE)
- Robert Schumann University of Music and Media (DE)
- Maastricht University (NL)
- Hôpital Cochin (FR)
- Manchester University NHS Foundation Trust (GB)
- Centre Hospitalier Territorial de Nouvelle-Calédonie (NC)
- Hospices Civils de Lyon (FR)
- University of Clermont Auvergne (FR)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- International Union of Railways (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- University Hospital of Geneva (CH)
- Azienda Ospedaliera San Gerardo (IT)
- Centre Hospitalier Compiègne-Noyon (FR)
- Istituto Ortopedico Gaetano Pini (IT)
- Centre Hospitalier du Mans (FR)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- A. O. Ordine Mauriziano di Torino (IT)
- Hôpital Louis Pradel (FR)
- Clinique Pasteur (FR)
- Hôpital Bichat-Claude-Bernard (FR)
- Clinique Saint Jean Languedoc (FR)
- Centre Hospitalier Intercommunal Toulon-La Seyne-sur-Mer (FR)
- ASST Fatebenefratelli Sacco (IT)
- Hôpital Manchester (FR)
- University of Florence (IT)
- Geneva College (US)
- University of Milano-Bicocca (IT)
- University of Algarve (PT)
- University of Brescia (IT)
- University of Palermo (IT)
- Université de Reims Champagne-Ardenne (FR)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- Journal of Internal Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1111/joim.70056
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00