Rumen microbiota–host interactions regulate intramuscular fat deposition in cattle via the alpha-linolenic acid–fatty acid β-oxidation/L-carnitine–MPO axis
This study reveals that Moheibacter, Cnuella, Gaetbulibacter, and Lacibacter play central regulatory roles in intramuscular fat deposition in beef cattle via the α-linolenic acid-fatty acid β-oxidation/L-carnitine-MPO axis. These findings highlight the critical role of microbial communities in regulating fat deposition through complex host-microbe interactions, providing insights for future strategies aimed at enhancing beef quality. Video Abstract.
Authors
- Mengcen Wang (ORCID: https://orcid.org/0000-0001-7169-6779)
- Gong Cheng (ORCID: https://orcid.org/0000-0003-0847-9004)
- Xiaoping He (ORCID: https://orcid.org/0000-0002-0697-6501)
- Wentao Zhang (ORCID: https://orcid.org/0000-0002-0903-3306)
- Chenyang Liu (ORCID: https://orcid.org/0000-0002-2564-1213)
- Linsen Zan (ORCID: https://orcid.org/0000-0002-2645-0179)
- Hongbao Wang (ORCID: https://orcid.org/0000-0002-5930-7037)
- C. S. Li
Institutions
- Agriculture and Forestry University (NP)
- North West Agriculture and Forestry University (CN)
- National Beef Cattle Industrial Technology System (CN)
- Northwest A&F University (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2025-12-10
- DOI
- https://doi.org/10.1186/s40168-025-02252-1
- Primary Topic
- Ruminant Nutrition and Digestive Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00