Impact of analytical treatment interruptions on sexual behaviors: a mixed-methods longitudinal study of women enrolled in an HIV cure–related trial in Durban, South Africa

For ATI-inclusive trials to reduce HIV transmission risk and social harms, investigators must understand contextual barriers perceived by participants who are expected to enact protective behaviors. Adaptive trial designs that incorporate participant-centered behavioral support, monitor and address emergent harms and facilitate prevention through access to HIV testing and PrEP for partners, must align with participants' evolving realities.

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Publication Details

Journal
HIV Research & Clinical Practice
Published
2025-12-09
DOI
https://doi.org/10.1080/25787489.2025.2599070
Citations
1
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
1.40
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article

Impact of analytical treatment interruptions on sexual behaviors: a mixed-methods longitudinal study of women enrolled in an HIV cure–related trial in Durban, South Africa

Vanessa Pillay, Karine Dubé, Maud Mthembu, Thumbi Ndung’u et al.
1 citations
HIV Research & Clinical Practice
HIV/AIDS Research and Interventions
1.40
article

Impact of analytical treatment interruptions on sexual behaviors: a mixed-methods longitudinal study of women enrolled in an HIV cure–related trial in Durban, South Africa

Vanessa Pillay, Karine Dubé, Maud Mthembu, Thumbi Ndung’u, Ayanda Zulu, Makhosonke Ngcobo, Jamila K. Stockman, Krista L. Dong, Luyanda Maphalala, Ali Ahmed, Fangping Wan, Maryam Hussain, Whitney Tran, Rachel Lau, Ntombifuthi Langa
article en
1 citations

Abstract

For ATI-inclusive trials to reduce HIV transmission risk and social harms, investigators must understand contextual barriers perceived by participants who are expected to enact protective behaviors. Adaptive trial designs that incorporate participant-centered behavioral support, monitor and address emergent harms and facilitate prevention through access to HIV testing and PrEP for partners, must align with participants' evolving realities.

HIV Research & Clinical PracticeVol. 26(1)
Harvard University (US), Ragon Institute of MGH, MIT and Harvard (US), University of California System (US), University of California San Diego (US), Massachusetts General Hospital (US), Africa Society for Blood Transfusion (ZA), Department of Animal Health (VN), Africa Health Research Institute (ZA), AIDS Vancouver (CA), Genesis Research Institute (JP), Umkhuseli Innovation and Research Management (ZA), Institute of Infection and Immunity (CA), University College London (GB), Mass General Brigham (US), University of KwaZulu-Natal (ZA)
Openalex Percentile: Top 14%
HIV/AIDS Research and Interventions
1.40
DOIOpen Access PDFOpenAlex
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