Cross-sectional and longitudinal associations between pan-immune-inflammation value and serum uric acid

PIV showed a nonlinear relationship with serum uric acid and hyperuricemia in cross-sectional analyses, while exhibiting a J-curve relationship in longitudinal studies. These suggest dynamic interactions between inflammatory markers and uric acid metabolism, dependent on inflammation duration.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-12-10
DOI
https://doi.org/10.3389/fendo.2025.1720450
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
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article

Cross-sectional and longitudinal associations between pan-immune-inflammation value and serum uric acid

Zilong Lu, Chang‐Sheng Sheng, Ling-Meng Wang, Jian Gong et al.
Frontiers in Endocrinology
Gout, Hyperuricemia, Uric Acid
article

Cross-sectional and longitudinal associations between pan-immune-inflammation value and serum uric acid

Zilong Lu, Chang‐Sheng Sheng, Ling-Meng Wang, Jian Gong, Yong Huo, Rui Chu, Yi Cheng
article en

Abstract

PIV showed a nonlinear relationship with serum uric acid and hyperuricemia in cross-sectional analyses, while exhibiting a J-curve relationship in longitudinal studies. These suggest dynamic interactions between inflammatory markers and uric acid metabolism, dependent on inflammation duration.

Frontiers in EndocrinologyVol. 16
Shanghai Institute of Hypertension (CN), Community Health Center (US)
Openalex Percentile: Top 51%
Gout, Hyperuricemia, Uric Acid
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