Comparative [18F]Florzolotau and [18F]FDG PET Imaging Patterns in Anti-IgLON5 Disease and Progressive Supranuclear Palsy
We identified distinct PET signatures that can reliably differentiate anti-IgLON5 disease from PSP. The complementary application of [18F]Florzolotau and [18F]FDG PET imaging may provide valuable biomarkers for differential diagnosis in clinically ambiguous cases, potentially enabling timely immunotherapeutic interventions for patients with imaging patterns suggestive of anti-IgLON5 disease.
Authors
- Zhao‐Xia Huang (ORCID: https://orcid.org/0000-0002-1569-5365)
- Menglin Liang
- Chenhao Jia
- Tianhao Zhang (ORCID: https://orcid.org/0000-0002-8765-0799)
- Han Wang (ORCID: https://orcid.org/0000-0002-7999-5180)
- Siyuan Fan (ORCID: https://orcid.org/0000-0001-8016-9110)
- Tzu‐Chen Yen
- Ruixue Cui (ORCID: https://orcid.org/0009-0000-8672-1885)
- Hongzhi Guan (ORCID: https://orcid.org/0000-0003-3903-5078)
- Qijun Li (ORCID: https://orcid.org/0000-0003-0635-9025)
Institutions
- Chinese Academy of Sciences (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1097/rlu.0000000000006155
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00