Amyloid Mimicking Myeloma: A Diagnostic Trap
Abstract We present the case of a 54-year-old male with relapsing multiple myeloma (MM) complicated by biopsy-proven amyloid deposition, monitored over a span of 13 years with serial 18F-FDG PET/CT imaging. The patient experienced multiple treatment interruptions and disease relapses, with evolving imaging features ranging from widespread skeletal involvement to soft tissue plasmacytoma formation and associated amyloid deposition. This case highlights the evolving role of 18F-FDG PET/CT in detecting disease progression and treatment response in plasma cell dyscrasias with coexisting amyloidosis.
Authors
- Sukanta Barai (ORCID: https://orcid.org/0000-0003-0641-3693)
- D. Sunitha
- Shivangi Dikshit (ORCID: https://orcid.org/0009-0002-4394-2447)
Institutions
- Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
Publication Details
- Journal
- World Journal of Nuclear Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1055/s-0045-1813680
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00