Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults
Among critically ill adults undergoing tracheal intubation, the use of ketamine to induce anesthesia did not result in a significantly lower incidence of in-hospital death by day 28 than etomidate. (Funded by the Patient-Centered Outcomes Research Institute and others; RSI ClinicalTrials.gov number, NCT05277896.).
Authors
- Benjamin Scott (ORCID: https://orcid.org/0000-0002-9723-9944)
- Jonathan D. Casey (ORCID: https://orcid.org/0000-0001-7188-4200)
- Daniel Resnick‐Ault (ORCID: https://orcid.org/0000-0002-7648-8319)
- Heidi L. Erickson (ORCID: https://orcid.org/0000-0001-5537-8893)
- J Gaillard (ORCID: https://orcid.org/0000-0001-8507-0566)
- Matthew W. Semler (ORCID: https://orcid.org/0000-0002-7664-8263)
- Jin H. Han (ORCID: https://orcid.org/0000-0003-0384-210X)
- Aaron E. Robinson (ORCID: https://orcid.org/0000-0002-9587-2973)
- Brant Imhoff (ORCID: https://orcid.org/0009-0006-7257-5673)
- Sheetal Gandotra (ORCID: https://orcid.org/0000-0002-5475-9704)
- Brian E. Driver (ORCID: https://orcid.org/0000-0002-7141-0256)
- Adit A. Ginde (ORCID: https://orcid.org/0000-0003-2325-206X)
- Stephanie C. DeMasi (ORCID: https://orcid.org/0000-0002-4149-8955)
- Neil R. Aggarwal (ORCID: https://orcid.org/0000-0002-0922-8824)
- Jason Brainard (ORCID: https://orcid.org/0000-0002-2125-868X)
- Wesley H. Self (ORCID: https://orcid.org/0000-0002-9300-3045)
- Kevin P. Seitz (ORCID: https://orcid.org/0000-0003-4686-5125)
- Tiffany Israel (ORCID: https://orcid.org/0000-0002-0852-8390)
- Jennifer J. McIntosh (ORCID: https://orcid.org/0000-0002-0299-9589)
- Stacy A. Trent (ORCID: https://orcid.org/0000-0001-9384-7400)
- Kevin W. Gibbs (ORCID: https://orcid.org/0000-0002-5272-2289)
- Todd W. Rice (ORCID: https://orcid.org/0000-0002-7136-5408)
- Micah R. Whitson (ORCID: https://orcid.org/0000-0001-5491-6661)
- Jessica A. Palakshappa (ORCID: https://orcid.org/0000-0002-6333-365X)
- Derek W. Russell (ORCID: https://orcid.org/0000-0002-2716-1344)
- Lauraine M. Stewart (ORCID: https://orcid.org/0000-0001-8218-6053)
- Alexandra B. Spicer (ORCID: https://orcid.org/0000-0001-9195-2143)
- David J. Douin (ORCID: https://orcid.org/0000-0002-5215-6854)
- Carolynn Lyle (ORCID: https://orcid.org/0000-0001-5083-6031)
- Tanya K. Marvi (ORCID: https://orcid.org/0000-0003-4976-4485)
- Matthew M. Churpek (ORCID: https://orcid.org/0000-0002-4030-5250)
- Kristen C. Sherlin
- Sarah Alber (ORCID: https://orcid.org/0009-0002-1155-1302)
- Angela Lewis
- Li Wang (ORCID: https://orcid.org/0000-0003-3722-5986)
- Matthew E. Prekker (ORCID: https://orcid.org/0000-0002-3969-3022)
- A. Muhs
- Logan L. Beach
- Bruce G. Redman
- B A Gould
- John P. Cain
- Aaron J. Lacy (ORCID: https://orcid.org/0000-0002-0467-6011)
- Bradley D. Lloyd
- Graham W. Van Schaik
Institutions
- St. Vincent's Birmingham (US)
- University of Wisconsin–Madison (US)
- Denver Health Medical Center (US)
- Hennepin County Medical Center (US)
- University of Alabama at Birmingham (US)
- VA Tennessee Valley Healthcare System (US)
- Geriatric Research Education and Clinical Center (US)
- Birmingham VA Medical Center (US)
- Denver School of Nursing (US)
- Wake Forest University (US)
- University of Colorado Anschutz Medical Campus (US)
- Vanderbilt University Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1056/nejmoa2511420
- Citations
- 9
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 19.72