Unique Sertoli cell adaptations support enhanced spermatogenesis in chickens
Our study revealed that the sustained proliferative capacity of Sertoli cells, their enriched signaling network, and the regulatory roles of CREB5 and circadian rhythms collectively represented unique testicular adaptations in chickens. These findings may hold extraordinary significance in understanding the molecular characteristics of poultry testicular development, and provide a plausible framework for explaining enhanced spermatogenesis in poultry.
Authors
- Ding He (ORCID: https://orcid.org/0000-0001-9620-6115)
- Jun Wang (ORCID: https://orcid.org/0000-0003-2873-384X)
- Yi Fang (ORCID: https://orcid.org/0000-0001-8675-4513)
- Wenfa Lu (ORCID: https://orcid.org/0000-0002-2417-1096)
- Gaoqing Xu (ORCID: https://orcid.org/0009-0002-1549-6427)
- Zhi‐Gang Gu (ORCID: https://orcid.org/0000-0003-3185-3906)
- Ziming Wang (ORCID: https://orcid.org/0000-0003-0714-4034)
- Jing Zhao (ORCID: https://orcid.org/0009-0009-0139-5538)
- Xin Ma (ORCID: https://orcid.org/0000-0003-2230-8973)
- Jing Guo (ORCID: https://orcid.org/0009-0008-0001-1240)
- Hongyu Liu (ORCID: https://orcid.org/0009-0002-6718-7976)
Institutions
- Anhui University of Science and Technology (CN)
- Jilin University (CN)
- Anhui Science and Technology University (CN)
- Jilin Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.1186/s40104-025-01304-8
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00