A Cyclic <i>tris</i> -BODIPY Complex Derived from Dithienopyrrole Embedded [48]Dodecaphyrin (1.0.0.1.0.0.1.0.0) as Photoacoustic Contrast Agent
A rigid dithienopyrrole embedded dodecaphyrin and its <i>tris</i>-BODIPY (bis(triisopropylsilyl-ethynyl)-substituted boron-dipyrromethene (BODIPY)) complex have been synthesized. DFT analysis showed a "<i>ruffled</i>" structure for dodecaphyrin and a <i>saddle</i>-shaped structure for <i>tris</i>-BODIPY. Increased conjugation of <i>tris</i>-BODIPY <b>2</b> showed a red-shifted absorption band (ca. 115 nm) with strong absorption in the NIR-I region as compared to its freebase analogue <b>1</b>. These optical features along with nonfluorescent characteristics of <b>2</b> displayed an efficient photoacoustic imaging contrast agent.
Authors
- Thondikkal Sulfikarali (ORCID: https://orcid.org/0000-0002-5563-5324)
- Deepayan Samanta (ORCID: https://orcid.org/0000-0002-6762-3101)
- Sabapathi Gokulnath (ORCID: https://orcid.org/0000-0001-9299-5217)
- Aathira Edwin (ORCID: https://orcid.org/0000-0003-0425-8116)
- Jayaprakash Ajay (ORCID: https://orcid.org/0000-0003-0525-9970)
- Mayanglambam Suheshkumar Singh (ORCID: https://orcid.org/0000-0002-1823-0846)
- Gayathri Krishnan (ORCID: https://orcid.org/0000-0002-1682-179X)
Institutions
- Indian Institute of Science Education and Research Thiruvananthapuram (IN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1021/acs.orglett.5c04304
- Primary Topic
- Luminescence and Fluorescent Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00