Pulmonary and Hepatic Echinococcosis with Eosinophilic Pneumonitis in an Expatriate Traveler

Echinococcus granulosus is a zoonotic parasitic disease that affects populations with endemic exposure in sheep-raising communities worldwide and is rarely observed in travelers. Humans become accidental intermediate hosts after inadvertently ingesting parasite eggs, which form progressively enlarging cysts, most commonly in the liver or lungs. Pulmonary cystic echinococcosis poses significant management challenges, as cyst rupture may result in anaphylaxis, broncho-pleural fistulas, and seeding of the thoracic cavity. Peripheral eosinophilia is a potential marker for cyst leakage and is associated with an increased risk of complications. A case of an expatriate traveler with hepatic and bilateral pulmonary echinococcosis, complicated by robust eosinophilic pneumonitis requiring emergent surgical intervention and prolonged corticosteroids, is presented in the current study.

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Publication Details

Journal
American Journal of Tropical Medicine and Hygiene
Published
2025-12-09
DOI
https://doi.org/10.4269/ajtmh.25-0233
Primary Topic
Parasitic infections in humans and animals
Type
article
Field-Weighted Citation Impact
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article

Pulmonary and Hepatic Echinococcosis with Eosinophilic Pneumonitis in an Expatriate Traveler

Pejman Radkani, Robert J. Varipapa, Roshanak Derakhshandeh, Adrienne Showler et al.
American Journal of Tropical Medicine and Hygiene
Parasitic infections in humans and animals
article

Pulmonary and Hepatic Echinococcosis with Eosinophilic Pneumonitis in an Expatriate Traveler

Pejman Radkani, Robert J. Varipapa, Roshanak Derakhshandeh, Adrienne Showler, Cristina Reichner, C Gauvin, Reena Jha, Marc Margolis, Andriy Kostyuk
article en

Abstract

Echinococcus granulosus is a zoonotic parasitic disease that affects populations with endemic exposure in sheep-raising communities worldwide and is rarely observed in travelers. Humans become accidental intermediate hosts after inadvertently ingesting parasite eggs, which form progressively enlarging cysts, most commonly in the liver or lungs. Pulmonary cystic echinococcosis poses significant management challenges, as cyst rupture may result in anaphylaxis, broncho-pleural fistulas, and seeding of the thoracic cavity. Peripheral eosinophilia is a potential marker for cyst leakage and is associated with an increased risk of complications. A case of an expatriate traveler with hepatic and bilateral pulmonary echinococcosis, complicated by robust eosinophilic pneumonitis requiring emergent surgical intervention and prolonged corticosteroids, is presented in the current study.

American Journal of Tropical Medicine and HygieneVol. 114(2)
MedStar Washington Hospital Center (US), Georgetown University (US), Washington Hospital (US), MedStar Georgetown University Hospital (US)
Openalex Percentile: Top 45%
Parasitic infections in humans and animals
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