Frequency and natural course of American College of Cardiology/American Heart Association valvular heart disease stages in the general population: results from the population-based STAAB cohort study
In a large community cohort, VHD was common, especially at older ages, and about 11% of individuals progressed within 3 years. Echocardiographic indices (E/e') and the biomarker NT-proBNP emerged as stage-specific predictors, supporting their potential role, along with age and metabolic factors, in identifying individuals at higher risk for progression.
Authors
- Lena Schmidbauer (ORCID: https://orcid.org/0000-0003-2606-8655)
- M Chen (ORCID: https://orcid.org/0009-0008-5941-3818)
- Floran Sahiti
- Peter U. Heuschmann (ORCID: https://orcid.org/0000-0002-2681-3515)
- Vladimir Cejka (ORCID: https://orcid.org/0000-0003-4393-1772)
- Götz Gelbrich
- Stefan Frantz (ORCID: https://orcid.org/0000-0002-0301-6185)
- Stefan Störk (ORCID: https://orcid.org/0000-0002-1771-7249)
- Caroline Morbach (ORCID: https://orcid.org/0000-0002-0920-6094)
Institutions
- University of Würzburg (DE)
- Universitätsklinikum Würzburg (DE)
Publication Details
- Journal
- Heart
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1136/heartjnl-2025-326443
- Citations
- 1
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Bundesministerium für Bildung und Forschung