Immunotherapy in Extensive Stage Small-Cell Lung Cancer in First-Line and Second-Line Setting

ICIs conferred efficacy benefits and an acceptable safety profile in the treatment of patients with ES-SCLC in the first-line, but should not be used in the second-line as single agents. Biomarkers predicting long-term benefit are needed to further improve outcomes.

Authors

Institutions

Publication Details

Journal
American Journal of Clinical Oncology
Published
2025-12-09
DOI
https://doi.org/10.1097/coc.0000000000001265
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Immunotherapy in Extensive Stage Small-Cell Lung Cancer in First-Line and Second-Line Setting

Jacques Raphael, Patsy Lee, Phillip Blanchette, Gabriel Boldt et al.
American Journal of Clinical Oncology
Lung Cancer Research Studies
article

Immunotherapy in Extensive Stage Small-Cell Lung Cancer in First-Line and Second-Line Setting

Jacques Raphael, Patsy Lee, Phillip Blanchette, Gabriel Boldt, Nupur Krishnan, Saurav Verma, Suganija Lakkunarajah
article en

Abstract

ICIs conferred efficacy benefits and an acceptable safety profile in the treatment of patients with ES-SCLC in the first-line, but should not be used in the second-line as single agents. Biomarkers predicting long-term benefit are needed to further improve outcomes.

American Journal of Clinical Oncology
Western University (CA), BC Cancer Agency (CA), London Health Sciences Centre (CA), Mount Vernon Cancer Centre (GB), Hamilton Health Sciences (CA), McMaster University (CA)
Openalex Percentile: Top 45%
Lung Cancer Research Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Immunotherapy in Extensive Stage Small-Cell Lung Cancer in First-Line and Second-Line Setting — Jacques Raphael, Patsy Lee, et al. · American Journal of Clinical Oncology (2025) | TGRS Research Map | TGRS