Imaging protoporphyrin IX photoproduct accumulation as a dosimetry reporter for monitoring photodynamic therapy of oral cancer
Overall, the results show that imaging of PP accumulation is feasible by adapting traditional photodiagnosis optical components and may serve as a dosimetry reporter for ALA-PDT, which is complementary to the measurement of PpIX photobleaching.
Authors
- Diana Merino Vega (ORCID: https://orcid.org/0000-0002-6173-6957)
- Mohammad A. Saad (ORCID: https://orcid.org/0000-0002-3337-2076)
- Bofan Song (ORCID: https://orcid.org/0000-0002-1171-8478)
- Tayyaba G. Hasan (ORCID: https://orcid.org/0000-0003-0871-6057)
- Rongguang Liang (ORCID: https://orcid.org/0000-0003-2792-3457)
- Shakir Khan (ORCID: https://orcid.org/0000-0002-2797-9592)
- Jonathan P. Celli (ORCID: https://orcid.org/0000-0003-3560-0770)
- Christian Liboy
Institutions
- Boston College (US)
- Harvard University (US)
- University of Arizona (US)
- University of Massachusetts Boston (US)
- Massachusetts General Hospital (US)
- Boston Engineering (United States) (US)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1117/1.jbo.30.s3.s34114
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dana-Farber/Harvard Cancer Center
- University of Massachusetts Boston
- National Institutes of Health
- National Cancer Institute