Physiological Normothermic Machine Perfusion Enhances Kidney Preservation Versus the Established UK Normothermic Machine Perfusion Assessment Protocol
The pNMP protocol improved preservation of donor kidneys compared to the cNMP protocol. Successful prolonged organ preservation could transform clinical kidney transplantation by obviating night-implantation and has further potential benefits for improving post-transplant outcomes and expanding the donor pool.
Authors
- Kavit Amin (ORCID: https://orcid.org/0000-0001-6545-7894)
- William G. Norton (ORCID: https://orcid.org/0000-0002-3731-0083)
- James E. Fildes (ORCID: https://orcid.org/0000-0001-9366-8955)
- Marc Clancy (ORCID: https://orcid.org/0000-0002-1709-9743)
- Emanuele Ricci (ORCID: https://orcid.org/0000-0001-9751-0661)
- William R. Cowey (ORCID: https://orcid.org/0009-0007-0388-1148)
- John P. Stone (ORCID: https://orcid.org/0000-0001-9452-2843)
- Timothy R. Entwistle
- Corban J. T. Bowers (ORCID: https://orcid.org/0009-0006-4970-553X)
- Amy F. Stewart (ORCID: https://orcid.org/0009-0003-6477-6465)
- Emily L. Milburn (ORCID: https://orcid.org/0009-0002-6883-9593)
- Georgina E. Chesworth (ORCID: https://orcid.org/0009-0002-6384-7658)
Institutions
- University of Liverpool (GB)
- Manchester Academic Health Science Centre (GB)
- NHS Greater Glasgow and Clyde (GB)
- University of Manchester (GB)
- Manchester University NHS Foundation Trust (GB)
- Cancer Research UK Manchester Institute (GB)
- Wythenshawe Hospital (GB)
- Queen Elizabeth University Hospital (GB)
Publication Details
- Journal
- Kidney360
- Published
- 2025-12-08
- DOI
- https://doi.org/10.34067/kid.0000001055
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00