Indeterminate Surgical Margins (Rx) in Renal Cell Carcinoma Surgery: Rates, Predictive Factors, and Impact on Overall Survival
Our study indicates that Rx should not be considered equivalent to R0 resection status, as it is associated with worse overall survival in RCC. These findings may aid in the postoperative risk assessment of RCC patients and guide clinical decision-making.
Authors
- Steven L. Chang (ORCID: https://orcid.org/0000-0002-7038-5861)
- José Ignacio Nolazco (ORCID: https://orcid.org/0000-0002-0239-6542)
- Edoardo Beatrici (ORCID: https://orcid.org/0000-0002-1209-2956)
- Dejan K. Filipas (ORCID: https://orcid.org/0000-0002-3671-3948)
- Toni K. Choueiri (ORCID: https://orcid.org/0000-0002-9201-3217)
- Michael Rink (ORCID: https://orcid.org/0000-0001-5403-7915)
- Muhieddine Labban (ORCID: https://orcid.org/0000-0002-4580-1915)
- Benjamin V. Stone (ORCID: https://orcid.org/0000-0002-3974-3667)
- Quoc‐Dien Trinh (ORCID: https://orcid.org/0000-0003-3857-9276)
- Alexander P. Cole (ORCID: https://orcid.org/0000-0002-0049-8529)
- Margit Fisch
- Shah P.D.
Institutions
- Brigham and Women's Hospital (US)
- Universität Hamburg (DE)
- Hospital Universitario Austral (AR)
- University Medical Center Hamburg-Eppendorf (DE)
- Dana-Farber Cancer Institute (US)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Clinical Genitourinary Cancer
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1016/j.clgc.2025.102481
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00