Glucose-to-lactate ratio in infants with hypoxic-ischemic encephalopathy treated with hypothermia

Glucose-to-lactate ratio did not predict neurodevelopmental outcome in infants with HIE treated with TH. Further investigation is needed to explore the prognostic significance of this biomarker. Glycemia and lactate blood levels measured at 24 h of TH, as well as cerebral MRI, are positively correlated with an increasing risk of unfavourable outcome.

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Publication Details

Journal
Early Human Development
Published
2025-12-09
DOI
https://doi.org/10.1016/j.earlhumdev.2025.106458
Primary Topic
Neonatal and fetal brain pathology
Type
article
Field-Weighted Citation Impact
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article

Glucose-to-lactate ratio in infants with hypoxic-ischemic encephalopathy treated with hypothermia

Carlo Dani, Elisa Scola, Clara Lunardi, Enrico Fainardi et al.
Early Human Development
Neonatal and fetal brain pathology
article

Glucose-to-lactate ratio in infants with hypoxic-ischemic encephalopathy treated with hypothermia

Carlo Dani, Elisa Scola, Clara Lunardi, Enrico Fainardi, Vittorio Miele, Giulia Remaschi, Caterina Coviello, Andrea Bianchi, Alessandra Cecchi, Camilla Fazi, Elia Benelli
article en

Abstract

Glucose-to-lactate ratio did not predict neurodevelopmental outcome in infants with HIE treated with TH. Further investigation is needed to explore the prognostic significance of this biomarker. Glycemia and lactate blood levels measured at 24 h of TH, as well as cerebral MRI, are positively correlated with an increasing risk of unfavourable outcome.

Early Human DevelopmentVol. 214
Azienda Ospedaliero-Universitaria Careggi (IT)
Openalex Percentile: Top 51%
Neonatal and fetal brain pathology
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Glucose-to-lactate ratio in infants with hypoxic-ischemic encephalopathy treated with hypothermia — Carlo Dani, Elisa Scola, et al. · Early Human Development (2025) | TGRS Research Map | TGRS