Research Progress of Artificial Intelligence Technology in Pharmacology of Traditional Chinese Medicine

In recent years, artificial intelligence (AI) technologies, particularly machine learning (ML) and deep learning (DL), have demonstrated significant potential in pharmacological research on traditional Chinese medicine (TCM). Due to the complexity of TCM compositions, targets, and pathways, conventional experimental methods encounter limitations in analyzing dose-response relationships and synergistic mechanisms. AI, with its advanced learning and data-processing capabilities, enables the integration of complex information, thereby enhancing the systematic approach, efficiency, and accuracy of research, and creating new opportunities for scientific discovery. This article reviews the latest progress in applying AI to TCM pharmacology, focusing on core algorithms, typical application scenarios, and future technological challenges, with the aim of providing theoretical support and methodological references for the modernization of TCM.

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Publication Details

Journal
Natural Product Communications
Published
2025-12-01
DOI
https://doi.org/10.1177/1934578x251405983
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Research Progress of Artificial Intelligence Technology in Pharmacology of Traditional Chinese Medicine

Xiaoming Zhou, Xinyu Liu, Jia Zhang, Guoying Wang et al.
Natural Product Communications
Computational Drug Discovery Methods
article

Research Progress of Artificial Intelligence Technology in Pharmacology of Traditional Chinese Medicine

Xiaoming Zhou, Xinyu Liu, Jia Zhang, Guoying Wang, Xiaoran Wang
article en

Abstract

In recent years, artificial intelligence (AI) technologies, particularly machine learning (ML) and deep learning (DL), have demonstrated significant potential in pharmacological research on traditional Chinese medicine (TCM). Due to the complexity of TCM compositions, targets, and pathways, conventional experimental methods encounter limitations in analyzing dose-response relationships and synergistic mechanisms. AI, with its advanced learning and data-processing capabilities, enables the integration of complex information, thereby enhancing the systematic approach, efficiency, and accuracy of research, and creating new opportunities for scientific discovery. This article reviews the latest progress in applying AI to TCM pharmacology, focusing on core algorithms, typical application scenarios, and future technological challenges, with the aim of providing theoretical support and methodological references for the modernization of TCM.

Natural Product CommunicationsVol. 20(12)
Wenzhou Medical University (CN), Shandong Provincial Hospital (CN), Xian Yang Central Hospital (CN), Dongyang People's Hospital (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 61%
Computational Drug Discovery Methods
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Research Progress of Artificial Intelligence Technology in Pharmacology of Traditional Chinese Medicine — Xiaoming Zhou, Xinyu Liu, et al. · Natural Product Communications (2025) | TGRS Research Map | TGRS