A Particular Case of Myocardial Injury

We report a case of a patient admitted to our coronary intensive care unit with chest pain and elevated cardiac troponin. Coronary angiography showed no obstructive coronary artery disease. The patient had a history of chronic rhinosinusitis and nasal polyps, treated with dupilumab. Laboratory tests revealed marked hypereosinophilia, prompting a cardiac MRI, which showed findings consistent with eosinophilic myocarditis. This diagnosis was later confirmed by endomyocardial biopsy. This case highlights the importance of differential diagnosis in cases of myocardial injury (characterized by increased cardiac troponin) and underscores the value of CMR as the most accurate non-invasive technique for detecting myocarditis.

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Publication Details

Journal
Diagnostics
Published
2025-12-09
DOI
https://doi.org/10.3390/diagnostics15243136
Primary Topic
Eosinophilic Disorders and Syndromes
Type
article
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article

A Particular Case of Myocardial Injury

Alessandra Scatteia, Enrica Pezzullo, Rita Gravino, Emilio Di Lorenzo et al.
Diagnostics
Eosinophilic Disorders and Syndromes
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A Particular Case of Myocardial Injury

Alessandra Scatteia, Enrica Pezzullo, Rita Gravino, Emilio Di Lorenzo, Paolo Golino, Daniele Masarone, Santo Dellegrottaglie, Francesco Loffredo, Luigi Falco, Antonia Ascrizzi, Dario Catapano
article en

Abstract

We report a case of a patient admitted to our coronary intensive care unit with chest pain and elevated cardiac troponin. Coronary angiography showed no obstructive coronary artery disease. The patient had a history of chronic rhinosinusitis and nasal polyps, treated with dupilumab. Laboratory tests revealed marked hypereosinophilia, prompting a cardiac MRI, which showed findings consistent with eosinophilic myocarditis. This diagnosis was later confirmed by endomyocardial biopsy. This case highlights the importance of differential diagnosis in cases of myocardial injury (characterized by increased cardiac troponin) and underscores the value of CMR as the most accurate non-invasive technique for detecting myocarditis.

DiagnosticsVol. 15(24)
University of Campania "Luigi Vanvitelli" (IT), Ospedale Monaldi (IT)
Openalex Percentile: Top 44%
Eosinophilic Disorders and Syndromes
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