Real-World Effectiveness and Tolerability of Low Dose Naltrexone to Treat Chronic Pain: A Retrospective Cohort Study of One Pain Physician’s Practice

These findings suggest that LDN may be an effective and well-tolerated treatment option for a range of chronic pain conditions. Further studies, such as randomized controlled trials, are warranted to confirm these results and optimize dosing strategies.

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Publication Details

Journal
Journal of Pain Research
Published
2025-12-01
DOI
https://doi.org/10.2147/jpr.s561662
Citations
2
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
3.76

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article

Real-World Effectiveness and Tolerability of Low Dose Naltrexone to Treat Chronic Pain: A Retrospective Cohort Study of One Pain Physician’s Practice

S.M. Paul, Heikki Aalto, Virginia McEwen
2 citations
Journal of Pain Research
Opioid Use Disorder Treatment
3.76
article

Real-World Effectiveness and Tolerability of Low Dose Naltrexone to Treat Chronic Pain: A Retrospective Cohort Study of One Pain Physician’s Practice

S.M. Paul, Heikki Aalto, Virginia McEwen
article en
2 citations

Abstract

These findings suggest that LDN may be an effective and well-tolerated treatment option for a range of chronic pain conditions. Further studies, such as randomized controlled trials, are warranted to confirm these results and optimize dosing strategies.

Journal of Pain ResearchVol. Volume 18
Thunder Bay Regional Health Sciences Centre (CA), St. Joseph's Care Group (CA), NOSM University (CA)
Northern Ontario Academic Medicine Association
Openalex Percentile: Top 6%
Opioid Use Disorder Treatment
3.76
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