Descemet's membrane endothelial keratoplasty with scraping without descemetorhexis (DMEK-SWD) in a failed penetrating keratoplasty
This pilot study demonstrates the feasibility of DMEK-SWD in treating failed PK, with a mean graft clearance time of 1.5 weeks for the two cases analyzed. The technique may represent a promising alternative to repeat full-thickness transplantation and supports further investigation in larger cohorts. Given the very small sample size and the incomplete availability of endothelial cell count data, these findings should be regarded as preliminary.
Authors
- Mohit Parekh (ORCID: https://orcid.org/0000-0002-5186-068X)
- Vito Romano (ORCID: https://orcid.org/0000-0002-5148-7643)
- Sabrina Vaccaro (ORCID: https://orcid.org/0000-0002-0881-1276)
- Francesco Semeraro (ORCID: https://orcid.org/0000-0002-2275-4917)
- Alexander Wallace (ORCID: https://orcid.org/0000-0002-5741-6424)
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
- Manchester University NHS Foundation Trust (GB)
- Surgical Specialties (Canada) (CA)
- Surgical Specialties (United States) (US)
- Smith-Kettlewell Eye Research Institute (US)
- University of Brescia (IT)
Publication Details
- Journal
- American Journal of Ophthalmology Case Reports
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1016/j.ajoc.2025.102499
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00