H-FABP and Hs-cTnI Serum Concentrations Associate with the Development of Cardiovascular Events in Newly Diagnosed T2D, Pre-DM, and Normoglycemic Individuals

These findings support H-FABP as a cardiac biomarker for myocardial injury across normoglycemic, Pre-DM, and T2D groups. The link between H-FABP and insulin resistance in individuals with greater burden of metabolic disturbance highlights its role as a cardiometabolic indicator. Both biomarkers predicted CVEs in asymptomatic individuals, with H-FABP potentially useful for early risk exclusion and Hs-cTnI for confirming high-risk status.

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Publication Details

Journal
Vascular Health and Risk Management
Published
2025-12-01
DOI
https://doi.org/10.2147/vhrm.s559031
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
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article

H-FABP and Hs-cTnI Serum Concentrations Associate with the Development of Cardiovascular Events in Newly Diagnosed T2D, Pre-DM, and Normoglycemic Individuals

Ranwa Alsayed, Reham Simon, Taghrid Hammoud
Vascular Health and Risk Management
Peroxisome Proliferator-Activated Receptors
article

H-FABP and Hs-cTnI Serum Concentrations Associate with the Development of Cardiovascular Events in Newly Diagnosed T2D, Pre-DM, and Normoglycemic Individuals

Ranwa Alsayed, Reham Simon, Taghrid Hammoud
article en

Abstract

These findings support H-FABP as a cardiac biomarker for myocardial injury across normoglycemic, Pre-DM, and T2D groups. The link between H-FABP and insulin resistance in individuals with greater burden of metabolic disturbance highlights its role as a cardiometabolic indicator. Both biomarkers predicted CVEs in asymptomatic individuals, with H-FABP potentially useful for early risk exclusion and Hs-cTnI for confirming high-risk status.

Vascular Health and Risk ManagementVol. Volume 21
Damascus University (SY)
Openalex Percentile: Top 64%
Peroxisome Proliferator-Activated Receptors
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