Ketamine for treatment resistant depression in individuals with eating disorders: a comparison study
In a population of individuals seeking higher level of care for an ED and controls matched for age, gender, sex, diagnosis, level of care, and race, treatment with ketamine was associated with significant reductions in depression and ED severity, but not more so than individuals not treated with ketamine. Findings from the study suggest that ketamine may be a viable treatment option for individuals with EDs, however, further research is needed to determine ketamine's efficacy in treating EDs with comorbid depression.
Authors
- Megan Riddle (ORCID: https://orcid.org/0000-0002-1162-9467)
- Dan V. Blalock (ORCID: https://orcid.org/0000-0002-8349-9825)
- Renee D. Rienecke (ORCID: https://orcid.org/0000-0003-0423-7403)
- Alan Duffy (ORCID: https://orcid.org/0000-0002-8697-9285)
- Phillip S. Mehler
- Elizabeth Wassenaar (ORCID: https://orcid.org/0000-0001-5555-3356)
- Anne O’Melia
- Howard Weeks
Institutions
- Seattle Pacific University (US)
- Duke University (US)
- University of Utah (US)
- Huntsman Cancer Institute (US)
- Northwestern University (PH)
- The Recovery Center (US)
- Durham VA Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of Eating Disorders
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1186/s40337-025-01448-y
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00