Identification of Co-Diagnostic Genes and Potential Therapeutic Targets for Asthma and Sepsis Through Mendelian Randomization and Immune Infiltration Analysis

<i>CXCL8</i> may be a biomarker for both asthma and sepsis. Immune cells like monocytes, macrophages, and T cells may drive comorbid progression. Potential drug candidates were identified, offering new insights for future research on these diseases.

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Publication Details

Journal
Journal of Asthma and Allergy
Published
2025-12-01
DOI
https://doi.org/10.2147/jaa.s550648
Primary Topic
Asthma and respiratory diseases
Type
article
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article

Identification of Co-Diagnostic Genes and Potential Therapeutic Targets for Asthma and Sepsis Through Mendelian Randomization and Immune Infiltration Analysis

Shukui Qin, Yuexiang Qin, Changhan Chen, Xupeng Zhang et al.
Journal of Asthma and Allergy
Asthma and respiratory diseases
article

Identification of Co-Diagnostic Genes and Potential Therapeutic Targets for Asthma and Sepsis Through Mendelian Randomization and Immune Infiltration Analysis

Shukui Qin, Yuexiang Qin, Changhan Chen, Xupeng Zhang, Shanhu Yao, Xinyi Li, Yuan Zhang, Meng Yang, Ming Hu, Yuyang Xiao
article en

Abstract

<i>CXCL8</i> may be a biomarker for both asthma and sepsis. Immune cells like monocytes, macrophages, and T cells may drive comorbid progression. Potential drug candidates were identified, offering new insights for future research on these diseases.

Journal of Asthma and AllergyVol. Volume 18
Central South University (CN), Shenzhen Children's Hospital (CN), Third Xiangya Hospital (CN), Xiangya Hospital Central South University (CN)
Openalex Percentile: Top 51%
Asthma and respiratory diseases
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Identification of Co-Diagnostic Genes and Potential Therapeutic Targets for Asthma and Sepsis Through Mendelian Randomization and Immune Infiltration Analysis — Shukui Qin, Yuexiang Qin, et al. · Journal of Asthma and Allergy (2025) | TGRS Research Map | TGRS