Comparative Finite Element Analysis of Denosumab and Bazedoxifene on Pedicle Screw Stability in Osteoporotic Spines
Finite element modeling suggested that Dmab enhanced pedicle screw fixation more effectively than BZA, particularly against axial and cranial/lateral-directed forces. These biomechanical differences underscore the potential advantage of Dmab in preoperative osteoporosis management to improve pedicle screw stability.
Authors
- Benjamin A. Alman (ORCID: https://orcid.org/0000-0002-7302-122X)
- Peter Gust Passias (ORCID: https://orcid.org/0000-0002-1479-4070)
- Masamichi Ishikawa
- Tomoyuki Asada (ORCID: https://orcid.org/0000-0003-3470-5546)
- Soji Tani
- Yoshifumi Kudo (ORCID: https://orcid.org/0000-0003-0469-3361)
- Koji Ishikawa (ORCID: https://orcid.org/0000-0003-3689-5662)
- Tomoko Towatari
- Philip Varnadore
Institutions
- SHOWA Medical University (JP)
- Hospital for Special Surgery (US)
- Duke University Hospital (US)
- SHOWA Medical University Hospital (JP)
Publication Details
- Journal
- JOR Spine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/jsp2.70147
- Primary Topic
- Spinal Fractures and Fixation Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science