Development of a Low-Cost Portable Iontophoresis Device

Hyperhidrosis, particularly of the palms and soles, is a common condition characterized by excessive and uncontrollable sweating that can significantly affect daily activities and quality of life. Among the many various treatments, the iontophoresis has emerged as a safe, simple, and non-pharmacological solution. Iontophoresis is used to treat excessive sweating (hyperhidrosis) by temporarily disabling sweat glands through a small direct current through the skin via water-filled electrodes. However, such devices are not widely available, and the price can range from hundreds to thousands of dollars. This study presents the design and working principle of a portable, low-cost iontophoresis device with a compact form factor suitable for home use. The system is powered by a standard USB power bank, providing long operating time, easy recharging, and improved portability compared to conventional mains-powered units. The prototype iontophoresis device is capable of delivering a controlled current of up to 25 mA. The device remained fully portable during use and operated reliably when powered from a standard USB power bank. As a functional observation of the system's current delivery, a noticeable difference in sweat reduction was observed between the two treated hands. Only the hand connected to the anode during all three sessions showed a marked decrease in sweating, while the other hand showed no measurable change. Commercial iontophoresis systems are often priced in the hundreds or even thousands of dollars despite being based on low-power electronic circuitry and readily available materials. Their high cost is influenced by factors such as regulatory approval requirements, safety testing, and limited market competition. The results of this work demonstrate that a functional, portable, and safe iontophoresis device can be produced at a fraction of this cost using basic components.

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Publication Details

Journal
Cureus
Published
2025-12-09
DOI
https://doi.org/10.7759/cureus.98797
Primary Topic
Sympathectomy and Hyperhidrosis Treatments
Type
article
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article

Development of a Low-Cost Portable Iontophoresis Device

Drin Rrmoku
Cureus
Sympathectomy and Hyperhidrosis Treatments
article

Development of a Low-Cost Portable Iontophoresis Device

Drin Rrmoku
article en

Abstract

Hyperhidrosis, particularly of the palms and soles, is a common condition characterized by excessive and uncontrollable sweating that can significantly affect daily activities and quality of life. Among the many various treatments, the iontophoresis has emerged as a safe, simple, and non-pharmacological solution. Iontophoresis is used to treat excessive sweating (hyperhidrosis) by temporarily disabling sweat glands through a small direct current through the skin via water-filled electrodes. However, such devices are not widely available, and the price can range from hundreds to thousands of dollars. This study presents the design and working principle of a portable, low-cost iontophoresis device with a compact form factor suitable for home use. The system is powered by a standard USB power bank, providing long operating time, easy recharging, and improved portability compared to conventional mains-powered units. The prototype iontophoresis device is capable of delivering a controlled current of up to 25 mA. The device remained fully portable during use and operated reliably when powered from a standard USB power bank. As a functional observation of the system's current delivery, a noticeable difference in sweat reduction was observed between the two treated hands. Only the hand connected to the anode during all three sessions showed a marked decrease in sweating, while the other hand showed no measurable change. Commercial iontophoresis systems are often priced in the hundreds or even thousands of dollars despite being based on low-power electronic circuitry and readily available materials. Their high cost is influenced by factors such as regulatory approval requirements, safety testing, and limited market competition. The results of this work demonstrate that a functional, portable, and safe iontophoresis device can be produced at a fraction of this cost using basic components.

CureusVol. 17(12)
University of Prishtina (XK)
Openalex Percentile: Top 51%
Sympathectomy and Hyperhidrosis Treatments
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Development of a Low-Cost Portable Iontophoresis Device — Drin Rrmoku · Cureus (2025) | TGRS Research Map | TGRS