Combined bone marrow mesenchymal stem cell-derived nanovesicles and low-level laser therapy potentiate proliferation and osteogenesis of bone marrow mesenchymal stem cells
This study proposes a novel cell-free therapeutic paradigm by synergistically integrating LLLT with BMSC-NVs, suggesting an effective bioengineering strategy for bone defect repair.
Authors
- Xin Liu (ORCID: https://orcid.org/0009-0007-9544-7188)
- Li-Huang Cui
- Xintao Wang (ORCID: https://orcid.org/0009-0002-8213-0556)
- Dailuo Li
- Y. J. Mo (ORCID: https://orcid.org/0009-0007-3362-7327)
- J J Chen (ORCID: https://orcid.org/0009-0008-1188-723X)
- Zhengye Zhang (ORCID: https://orcid.org/0009-0008-1558-827X)
- Jingwei Zhang (ORCID: https://orcid.org/0000-0003-1980-5442)
- Weitao He
- Zhibin Geng
- Qi Han (ORCID: https://orcid.org/0000-0002-9418-807X)
- Tonghao Yao
Institutions
- Weifang Medical University (CN)
- Harbin Medical University (CN)
- Second Hospital of Shandong University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fbioe.2025.1676777
- Citations
- 1
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Natural Science Foundation of Heilongjiang Province