Innovative approach in Parkinson’s targeting via berberine-loaded mucoadhesive surface-modified liposomes: a multi-faceted study
Our findings imply that BER chitosomes are a viable intranasal delivery tool for the efficient treatment of PD due to their enhanced bioavailability. and greater nasal mucosa penetration.
Authors
- Hend A. Sharafeldin
- Mona Elharoun (ORCID: https://orcid.org/0000-0001-6610-8717)
- Haidy Abbas
- Amr Elkelish (ORCID: https://orcid.org/0000-0002-1683-8436)
- Manal A Elsheikh (ORCID: https://orcid.org/0000-0001-5704-2429)
- Fathy Elsayed Abdelgawad (ORCID: https://orcid.org/0000-0002-4958-1761)
- Komla Mawunyo Dossouvi (ORCID: https://orcid.org/0000-0003-0967-5314)
- Hisham A. Nematalla (ORCID: https://orcid.org/0000-0002-7218-4115)
- Amir E. Mehana (ORCID: https://orcid.org/0000-0001-9421-4090)
- Mariam Zewail (ORCID: https://orcid.org/0000-0002-1930-9361)
- Mohammad Mahmoud Abd-Alhaseeb (ORCID: https://orcid.org/0000-0001-5388-5250)
Institutions
- University of Vermont (US)
- Suez Canal University (EG)
- Damanhour University (EG)
- Imam Mohammad ibn Saud Islamic University (SA)
- AlAlamein International University (EG)
- Islamic University of Madinah (SA)
- University of Lomé (TG)
- Alexandria University (EG)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1186/s40360-025-01039-2
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00