Chinese expert consensus on diagnosis and treatment of small gastrointestinal stromal tumors (2025 edition)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, with malignant potential ranging from very low risk to high risk. Small GISTs, defined as those with measuring <2 cm in greatest dimension, generally exhibit benign or indolent behavior, although a few exhibit aggressive features. The evidence of epidemiology, biologic behavior, diagnosis, treatment, and surveillance of small GISTs is limited, and the treatment status in clinical practice has no uniform standards. Thus the Chinese Society of Clinical Oncology Expert Committee on Gastrointestinal Stromal Tumor systemically reviewed the latest evidence using the Delphi method and provided recommendations for diagnosing and treating small GISTs.
Authors
- Liming Zhang (ORCID: https://orcid.org/0000-0001-8086-9133)
- Ye Zhou (ORCID: https://orcid.org/0000-0002-8780-0099)
- Yan Kui Sun (ORCID: https://orcid.org/0000-0001-8916-9598)
- Shukui Qin (ORCID: https://orcid.org/0000-0003-2289-1521)
- Yingjiang Ye (ORCID: https://orcid.org/0000-0002-7904-3163)
- Lin Shen (ORCID: https://orcid.org/0000-0002-8798-4756)
- Yulong He (ORCID: https://orcid.org/0000-0002-1902-0963)
- Yong Li (ORCID: https://orcid.org/0000-0003-1799-4841)
- Tao Chen (ORCID: https://orcid.org/0000-0002-8371-779X)
- Peng Zhang (ORCID: https://orcid.org/0000-0003-1771-7545)
- Jian Li (ORCID: https://orcid.org/0000-0002-9333-3255)
- Chao Wang (ORCID: https://orcid.org/0009-0001-3192-253X)
- Ming Wang (ORCID: https://orcid.org/0009-0001-1922-6363)
- Shijie Li (ORCID: https://orcid.org/0000-0003-4854-6590)
- Han Liang (ORCID: https://orcid.org/0000-0003-0457-2877)
- Yi Wang (ORCID: https://orcid.org/0000-0002-7000-693X)
- Xin Wu (ORCID: https://orcid.org/0000-0002-3839-4768)
- Hui Cao (ORCID: https://orcid.org/0000-0002-5901-5499)
- Haoran Qian
- Zhidong Gao (ORCID: https://orcid.org/0009-0002-8120-1420)
- Bo Zhang (ORCID: https://orcid.org/0000-0002-4738-0704)
Institutions
- Hebei Medical University (CN)
- Union Hospital (HK)
- Sun Yat-sen University (CN)
- Peking University (CN)
- Sichuan University (CN)
- Renji Hospital (CN)
- Sir Run Run Shaw Hospital (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Chinese General Hospital College of Nursing and Liberal Arts (PH)
- West China Hospital of Sichuan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Peking University Cancer Hospital (CN)
- People's Liberation Army No. 150 Hospital (CN)
- Hospital 463 People's Liberation Army (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Peking University People's Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Ministry of Education (ET)
- Chinese People's Liberation Army (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Huazhong University of Science and Technology (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Cancer
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/cncr.70152
- Primary Topic
- Gastrointestinal Tumor Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China