Arecoline upregulates CD155 expression to facilitate immune evasion in oral squamous cell carcinoma
This study unveils a novel mechanism by which arecoline promotes immune evasion in OSCC and highlights promising immune therapeutic targets and strategies for the treatment of areca nut-associated OSCC.
Authors
- Pan Chen (ORCID: https://orcid.org/0000-0001-7392-8262)
- Zhaojian Gong (ORCID: https://orcid.org/0000-0001-7501-3613)
- Zhaoyang Zeng
- Junshang Ge
- Bo Xiang (ORCID: https://orcid.org/0000-0003-2641-5434)
- Ming Zhou (ORCID: https://orcid.org/0000-0003-4938-5397)
- Qian Wang (ORCID: https://orcid.org/0000-0003-2109-1725)
- Shanshan Zhang (ORCID: https://orcid.org/0000-0002-4566-6928)
- Yuhang Liu (ORCID: https://orcid.org/0000-0001-9151-5146)
- Wei Xiong (ORCID: https://orcid.org/0000-0003-1635-8173)
- Yi Meng
- Yian Wang (ORCID: https://orcid.org/0009-0002-9268-0527)
Institutions
- Central South University (CN)
- Ministry of Education (SA)
- Hunan Cancer Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/jitc-2025-012982
- Citations
- 1
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47