HPV genotype distribution and cervical lesion severity in HPV-positive women: a study from the Guizhou Province cervical cancer screening program
HPV16 predominates across the entire cervical lesion spectrum, with its prevalence significantly increasing with lesion severity. Furthermore, the nonavalent HPV vaccine covers all prevalent oncogenic hrHPV genotypes in this region (except for HPV56). These findings provide crucial epidemiological evidence for optimizing HPV vaccination strategies and cervical cancer screening programs.
Authors
- Xingjing Luo (ORCID: https://orcid.org/0000-0001-5952-8721)
- Lei He (ORCID: https://orcid.org/0000-0001-6941-2466)
- Ying Qing Chen (ORCID: https://orcid.org/0000-0002-2726-3391)
- Fei Zhang (ORCID: https://orcid.org/0000-0002-4032-5913)
- Honghong Zhang (ORCID: https://orcid.org/0000-0003-1878-8126)
- Bing Liu (ORCID: https://orcid.org/0000-0003-3578-1030)
- Qi Fan (ORCID: https://orcid.org/0000-0002-9122-4426)
- Sihan Liu (ORCID: https://orcid.org/0009-0005-2358-877X)
Institutions
- The First People's Hospital of Guiyang (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1186/s12985-025-03041-w
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00