Genomic Characterization of Intestinal Colonizing Pseudomonas juntendi Strains Harboring blaVIM-2
This study reports two clonally related <i>P. juntendi</i> strains harboring <i>bla</i> <sub>VIM-2</sub> isolated from human fecal microbiota, expanding the genomic understanding of carbapenem-resistant <i>P. juntendi</i>. The close phylogenetic relationship between these human isolates and an animal-derived strain (<i>P. juntendi</i> yb_3) underscores bidirectional resistance gene flow at the human-animal interface. Our findings support a One Health-oriented surveillance approach to mitigate the dissemination of carbapenemase-producing pathogens.
Authors
- Huanran Zhang
- Ruishan Liu (ORCID: https://orcid.org/0000-0002-7298-0701)
- Lei Fang (ORCID: https://orcid.org/0000-0003-3999-7170)
- Yi Liu (ORCID: https://orcid.org/0000-0003-0548-6073)
- Weidong Zhu (ORCID: https://orcid.org/0000-0003-3359-3394)
- Junli Zhang (ORCID: https://orcid.org/0000-0003-1650-1048)
Institutions
- Shaoxing University (CN)
- Wenzhou Medical University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/idr.s554163
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China