Social stress, cortisol awakening response and sex: association with hippocampus and amygdala volume
The association between chronic social stress and HC and AMY volume is interacting with CAR-pattern and sex. The brain morphology in males and in individuals with an atypical CAR showed reductions in association with chronic social stress. Our findings point to a complex interaction between social stress, cortisol patterns, sex and brain architecture, which needs to be assessed in more detail in future research.
Authors
- Leandra Kuhn (ORCID: https://orcid.org/0000-0003-1592-5420)
- Hannes Noack (ORCID: https://orcid.org/0000-0002-1873-0867)
- Ute Habel (ORCID: https://orcid.org/0000-0003-0703-7722)
- Birgit Derntl (ORCID: https://orcid.org/0000-0003-0133-4486)
- Vanessa Nieratschker (ORCID: https://orcid.org/0000-0001-7884-4500)
- Lydia Kogler (ORCID: https://orcid.org/0000-0002-9493-2321)
- Rui Wang (ORCID: https://orcid.org/0000-0001-9293-6452)
Institutions
- BG Klinik Tübingen (DE)
- German Center for Infection Research (DE)
- University of Tübingen (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1186/s13293-025-00801-9
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Eberhard Karls Universität Tübingen
- China Scholarship Council