Genomic and functional characterization of the L‑sorbose phosphotransferase system in high-risk <i>Escherichia coli</i> lineages
This study highlights the value of combining large-scale genomic analyses with functional validation for identifying and analyzing the L‑sorbose phosphotransferase system in different <i>E. coli</i> high-risk clones. This knowledge may be applied in future studies to address the need for identifying alternative, pathogen-specific targets.
Authors
- Katharina Schaufler (ORCID: https://orcid.org/0000-0002-2669-8799)
- Christian Hentschker
- Lena-Sophie Swiatek (ORCID: https://orcid.org/0009-0007-2543-8403)
- Elias Eger (ORCID: https://orcid.org/0000-0002-5514-8083)
- Kristin Surmann (ORCID: https://orcid.org/0009-0009-7305-3457)
- Lukas Schulig (ORCID: https://orcid.org/0000-0002-4614-3395)
- Michael Schwabe (ORCID: https://orcid.org/0009-0006-8098-9841)
- Uwe Völker (ORCID: https://orcid.org/0000-0002-5689-3448)
- Thaddäus Echelmeyer
- Marco Harms
- Fynn Meller
Institutions
- Universitätsmedizin Greifswald (DE)
- Universität Greifswald (DE)
- Helmholtz Centre for Infection Research (DE)
Publication Details
- Journal
- mSystems
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1128/msystems.01274-25
- Primary Topic
- Bacterial Genetics and Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 0.00