Adolescent “Lean PCOS” Is Characterized by Higher Insulin Resistance and Adverse Adipokine Profile
Within this population-based cohort, adolescents with PCOS and BMI <85th percentile had greater insulin resistance and adipose tissue dysfunction vs without PCOS. PCOS-associated metabolic dysfunction exist even among adolescents with BMI <85th percentile.
Authors
- Izzuddin M. Aris (ORCID: https://orcid.org/0000-0002-9239-7476)
- Sheryl L. Rifas‐Shiman (ORCID: https://orcid.org/0000-0003-0033-920X)
- Wei Perng (ORCID: https://orcid.org/0000-0001-8552-6850)
- Marie‐France Hivert (ORCID: https://orcid.org/0000-0001-7752-2585)
- Jorge E. Chavarro (ORCID: https://orcid.org/0000-0002-4436-9630)
- Rachel Whooten (ORCID: https://orcid.org/0000-0002-6845-4821)
- Emily Oken
Institutions
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Harvard University (US)
- Colorado School of Public Health (US)
- Massachusetts General Hospital (US)
- Harvard Pilgrim Health Care (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1210/clinem/dgaf606
- Citations
- 1
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.70