Pretreatment Amide Proton Transfer‐Weighted Imaging Histogram Analysis Combined With <scp>ER</scp> ‐Negative and <scp>HER2</scp> ‐Positive Expression Predicts Pathologic Complete Response After Neoadjuvant Chemotherapy in Breast Cancer
Pre-treatment histogram analysis of MTRasym values derived from APTWI provides significant predictive value for pCR post-NAC in breast cancer. The combined diagnostic model incorporating APTWI with ER and HER2 expression status further enhances diagnostic performance.
Authors
- Yue Wu (ORCID: https://orcid.org/0000-0002-4507-9782)
- Chunmiao Xu (ORCID: https://orcid.org/0000-0003-4064-5447)
- Renzhi Zhang (ORCID: https://orcid.org/0000-0001-7723-0865)
- Jinrong Qu (ORCID: https://orcid.org/0000-0001-8751-9988)
- Zhiwei Shen (ORCID: https://orcid.org/0009-0003-8348-8303)
- Jing Li (ORCID: https://orcid.org/0000-0002-2169-1512)
- Mingzhe Xu (ORCID: https://orcid.org/0000-0002-1757-6773)
- Xuejun Chen (ORCID: https://orcid.org/0000-0001-6124-7312)
- Dongqiu Shan
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Philips (China) (CN)
- National Cancer Center (US)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/cam4.71420
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00