Intrinsic Versus Extrinsic Sinus and Atrioventricular Nodes Dysfunction in Athletes: Insights From Transesophageal Electrophysiological Testing With Autonomic Blockade

The EPS with a pharmacological autonomic blockade represents a useful approach for distinguishing extrinsic, functional bradycardia from intrinsic nodal disease in athletes. While AV node dysfunction appears exclusively vagally mediated and reversible, a subset of sinus node dysfunction cases may reflect early, possibly epigenetically driven, intrinsic alterations.

Authors

Institutions

Publication Details

Journal
Reviews in Cardiovascular Medicine
Published
2025-11-27
DOI
https://doi.org/10.31083/rcm42738
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Intrinsic Versus Extrinsic Sinus and Atrioventricular Nodes Dysfunction in Athletes: Insights From Transesophageal Electrophysiological Testing With Autonomic Blockade

Sergei Bondarev, Alessandro Zorzi, Domenico Corrado
Reviews in Cardiovascular Medicine
Cardiac Arrhythmias and Treatments
article

Intrinsic Versus Extrinsic Sinus and Atrioventricular Nodes Dysfunction in Athletes: Insights From Transesophageal Electrophysiological Testing With Autonomic Blockade

Sergei Bondarev, Alessandro Zorzi, Domenico Corrado
article en

Abstract

The EPS with a pharmacological autonomic blockade represents a useful approach for distinguishing extrinsic, functional bradycardia from intrinsic nodal disease in athletes. While AV node dysfunction appears exclusively vagally mediated and reversible, a subset of sinus node dysfunction cases may reflect early, possibly epigenetically driven, intrinsic alterations.

Reviews in Cardiovascular MedicineVol. 26(11)
University of Padua (IT), St Petersburg University (RU), Federal State Budget Educational Institution of Higher Education «Lesgaft National State University of Physical Education, Sport and Health, St. Petersburg» (RU)
Openalex Percentile: Top 44%
Cardiac Arrhythmias and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.