Adolescent binge drinking causes sex-specific deficits in behavioral reactivity, endocrine recovery from stress and altered expression of hypothalamic KCC2 in males
Taken together, these data show that adolescent binge drinking in pair-housed mice is associated with male-specific potential vulnerability in hypothalamic inhibitory signaling and disrupted adult stress reactivity in a sex- and stressor- dependent manner.
Authors
- Marianne Benn (ORCID: https://orcid.org/0000-0002-1701-595X)
- Laverne C. Melón (ORCID: https://orcid.org/0000-0002-2256-3707)
- Bilge Büyükdemirtaş
- Han Bin Kwon
- E. Rosen
Institutions
- Wesleyan University (US)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1007/s00213-025-06969-7
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00