Depigmentation Therapy of Refractory Facial Vitiligo Using 532‐Nm Picosecond Laser: Two Case Reports and Literature Review

The 532-nm picosecond laser, followed by topical hydroquinone, appears to be an effective and well-tolerated approach for managing residual pigmentation in vitiligo. This reverse depigmentation strategy may serve as a valuable adjunct to enhance skin tone uniformity in selected patients.

Authors

Xinxin Li (ORCID: https://orcid.org/0000-0001-8044-6931)
Juan Du (ORCID: https://orcid.org/0000-0002-1850-3613)
Xiaolan Ding (ORCID: https://orcid.org/0000-0001-9044-784X)
Fang Wang (ORCID: https://orcid.org/0000-0003-1752-2449)
X. Q. Yuan (ORCID: https://orcid.org/0009-0002-7391-5917)

Institutions

Peking University (CN)
Peking University People's Hospital (CN)

Publication Details

Journal: Journal of Cosmetic Dermatology
Published: 2025-12-01
DOI: https://doi.org/10.1111/jocd.70604
Primary Topic: melanin and skin pigmentation
Type: article
Field-Weighted Citation Impact: 0.00

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article

Depigmentation Therapy of Refractory Facial Vitiligo Using 532‐Nm Picosecond Laser: Two Case Reports and Literature Review

Xinxin Li, Juan Du, Xiaolan Ding, Fang Wang et al.

Dec 1, 2025

Journal of Cosmetic Dermatology

melanin and skin pigmentation

article

Depigmentation Therapy of Refractory Facial Vitiligo Using 532‐Nm Picosecond Laser: Two Case Reports and Literature Review

Xinxin Li, Juan Du, Xiaolan Ding, Fang Wang, X. Q. Yuan

December 1, 2025article en

Abstract

The 532-nm picosecond laser, followed by topical hydroquinone, appears to be an effective and well-tolerated approach for managing residual pigmentation in vitiligo. This reverse depigmentation strategy may serve as a valuable adjunct to enhance skin tone uniformity in selected patients.

Journal of Cosmetic DermatologyVol. 24(12)

Peking University (CN), Peking University People's Hospital (CN)

Openalex Percentile: Top 59%

melanin and skin pigmentation

DOI Open Access PDF OpenAlex

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Depigmentation Therapy of Refractory Facial Vitiligo Using 532‐Nm Picosecond Laser: Two Case Reports and Literature Review — Xinxin Li, Juan Du, et al. · Journal of Cosmetic Dermatology (2025) | TGRS Research Map | TGRS