Brain aging: molecular targets of geroprotection and prevention strategies

The article provides an overview of domestic and foreign literature on the relevance of developing and implementing comprehensive medical and social methods for the prevention and treatment of gerontological pathologies. It examines the morphological and biochemical foundations of brain aging and presents methods for pharmacological correction of these changes. The use of the original domestic drug, the breadth of therapeutic effects of the drug ethylmethylhydroxypyridine succinate (Meksidol), based on its biochemical mechanisms of action, its high clinical efficacy, and the favorable safety profile of Meksidol in the absence of drug interactions, make its use promising in the comprehensive treatment of older patients.

Authors

Institutions

Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2025-12-09
DOI
https://doi.org/10.17116/jnevro2025125111132
Primary Topic
Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Brain aging: molecular targets of geroprotection and prevention strategies

E I Chukanova, A S Chukanova
S S Korsakov Journal of Neurology and Psychiatry
Neurological Disorders and Treatments
article

Brain aging: molecular targets of geroprotection and prevention strategies

E I Chukanova, A S Chukanova
article en

Abstract

The article provides an overview of domestic and foreign literature on the relevance of developing and implementing comprehensive medical and social methods for the prevention and treatment of gerontological pathologies. It examines the morphological and biochemical foundations of brain aging and presents methods for pharmacological correction of these changes. The use of the original domestic drug, the breadth of therapeutic effects of the drug ethylmethylhydroxypyridine succinate (Meksidol), based on its biochemical mechanisms of action, its high clinical efficacy, and the favorable safety profile of Meksidol in the absence of drug interactions, make its use promising in the comprehensive treatment of older patients.

S S Korsakov Journal of Neurology and PsychiatryVol. 125(11)
Pirogov Russian National Research Medical University (RU)
Openalex Percentile: Top 54%
Neurological Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Brain aging: molecular targets of geroprotection and prevention strategies — E I Chukanova, A S Chukanova · S S Korsakov Journal of Neurology and Psychiatry (2025) | TGRS Research Map | TGRS