Acute severe cholestatic hepatitis and lymphopenia characterize pediatric hepatitis‐associated aplastic anemia

HAAA occurs in both SAA and RCC. Most cases present with severe acute cholestatic hepatitis and variable coagulopathy. Hepatic recovery is common. Lymphopenia at disease onset is frequent and may serve as a diagnostic marker.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2025-12-09
DOI
https://doi.org/10.1002/jpn3.70308
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute severe cholestatic hepatitis and lymphopenia characterize pediatric hepatitis‐associated aplastic anemia

Jan Beime, Sofia Tsaka, Jun Oh, Kai Lehmberg et al.
Journal of Pediatric Gastroenterology and Nutrition
Hematopoietic Stem Cell Transplantation
article

Acute severe cholestatic hepatitis and lymphopenia characterize pediatric hepatitis‐associated aplastic anemia

Jan Beime, Sofia Tsaka, Jun Oh, Kai Lehmberg, Daniel Tegtmeyer, Sebastian Schulz‐Jürgensen, Andrea Briem‐Richter, Elke Lainka, Michaela Höfs
article en

Abstract

HAAA occurs in both SAA and RCC. Most cases present with severe acute cholestatic hepatitis and variable coagulopathy. Hepatic recovery is common. Lymphopenia at disease onset is frequent and may serve as a diagnostic marker.

Journal of Pediatric Gastroenterology and NutritionVol. 82(2)
Universität Hamburg (DE), German Climate Computing Centre (DE), University Medical Center Hamburg-Eppendorf (DE), Kinderkrebs-Zentrum Hamburg (DE), ERN GUARD-Heart (NL), University of Duisburg-Essen (DE)
Openalex Percentile: Top 41%
Hematopoietic Stem Cell Transplantation
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