Gait disorders patients with patients with cerebral microangiopathy: association with the microstructural integrity of the tracts involved in walking
Impaired ambulation and associated fall risk are common in patients with CMA. Microstructural damage (assessed by FA) of the frontopontine and corticoreticulospinal tracts, mainly at the level of subcortical and deep white matter, is crucial for the development of impaired ambulation and fall risk. The obtained FA threshold values of these tracts can be used as objective markers to identify patients at high risk of impaired ambulation and fall risk in the early stages, which is essential for timely prevention.
Authors
- Elina T. Bitsieva (ORCID: https://orcid.org/0000-0003-1464-0722)
- М. В. Кротенкова (ORCID: https://orcid.org/0000-0003-3820-4554)
- Еlena I. Kremneva (ORCID: https://orcid.org/0000-0001-9396-6063)
- Кamila V. Shamtieva (ORCID: https://orcid.org/0000-0002-6995-1352)
- A. S. Filatov (ORCID: https://orcid.org/0000-0002-5706-6997)
- Л А Добрынина (ORCID: https://orcid.org/0000-0001-9929-2725)
- Anastasia A. Geints (ORCID: https://orcid.org/0009-0001-1836-2515)
- V.O. Belousov (ORCID: https://orcid.org/0009-0005-7337-9087)
- I.M. Egerev (ORCID: https://orcid.org/0009-0009-7449-4449)
Institutions
- Lomonosov Moscow State University (RU)
- Moscow State University (TJ)
- Research Center of Neurology (RU)
Publication Details
- Journal
- S S Korsakov Journal of Neurology and Psychiatry
- Published
- 2025-12-09
- DOI
- https://doi.org/10.17116/jnevro2025125111123
- Primary Topic
- Balance, Gait, and Falls Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00