Exploring the Mechanism of CaoHuangGuiXiang Formula in Ameliorating Systemic Candida albicans Infection: A Study Integrating Network Pharmacology and Animal Experiments
This study elucidates the potential multi-pathway and multi-target mechanisms underlying the therapeutic efficacy of the CHGX formula against <i>Candida</i> infectious diseases, indicating its potential as a novel alternative antifungal drug and providing a scientific basis for its clinical application and further development.
Authors
- Yi Bai (ORCID: https://orcid.org/0000-0002-1179-3734)
- Shuhua Liu (ORCID: https://orcid.org/0000-0002-0088-6177)
- Qingquan Liu (ORCID: https://orcid.org/0000-0003-0828-0361)
- Wenjing Zhu (ORCID: https://orcid.org/0000-0003-0958-0905)
- Huizhen Yue (ORCID: https://orcid.org/0009-0001-4618-308X)
- Xiaolong Xu
- Jinhao Tian
Institutions
- Beijing University of Chinese Medicine (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
- Institute of Infection and Immunity (CA)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jir.s551135
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00