Exploring Carbon Dot Nanoparticles for Imaging and Cellular Interaction in Triple-Negative Breast Cancer
These results show that although E-CNDs appear non-toxic by standard viability assays and function effectively as imaging agents, they also trigger measurable molecular and apoptotic responses. This underscores that cell viability alone is insufficient to assume biocompatibility. More detailed molecular and functional assessments are needed to establish reliable safety profiles, which are critical for the safe design and evaluation of nanomaterials in biomedical applications.
Authors
- Reza M. Zadegan (ORCID: https://orcid.org/0000-0001-9662-7331)
- Kerui Wu (ORCID: https://orcid.org/0000-0002-5504-8875)
- Jianjun Wei (ORCID: https://orcid.org/0000-0002-2658-0248)
- Mehrnoosh Bahadorani (ORCID: https://orcid.org/0000-0002-5825-1086)
Institutions
- University of North Carolina at Greensboro (US)
- North Carolina Agricultural and Technical State University (US)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijn.s544373
- Primary Topic
- Carbon and Quantum Dots Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Institutes of Health