Unveiling unusual radiological findings: Breast volume reduction in patients with pregnancy associated breast cancer: A case series of three patients

Diagnosis of Pregnancy-associated breast cancer (PABC) is challenging and often misdiagnosed as benign breast disease due to physiological changes during pregnancy or lactation.A delay in diagnosis and management stems from concerns for the fetus and newborn, especially in our social context. PABC patients typically present with breast lumps and enlargement on examination, and masses on imaging. Reduction of breast glandular tissue volume is rare in breast cancer, and few case reports of breast cancer with breast shrinkage are reported in the literature, which were not pregnancy-associated. We are presenting a series of three cases of PABC where we observed ipsilateral breast shrinkage with reduction of fibroglandular tissue as unusual radiological findings in these patients.

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Publication Details

Journal
Asian Journal of Oncology
Published
2025-12-09
DOI
https://doi.org/10.25259/asjo_42_2025
Primary Topic
Cancer Risks and Factors
Type
article
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article

Unveiling unusual radiological findings: Breast volume reduction in patients with pregnancy associated breast cancer: A case series of three patients

Asmita, Gyan Chand, Abhraneel Das
Asian Journal of Oncology
Cancer Risks and Factors
article

Unveiling unusual radiological findings: Breast volume reduction in patients with pregnancy associated breast cancer: A case series of three patients

Asmita, Gyan Chand, Abhraneel Das
article en

Abstract

Diagnosis of Pregnancy-associated breast cancer (PABC) is challenging and often misdiagnosed as benign breast disease due to physiological changes during pregnancy or lactation.A delay in diagnosis and management stems from concerns for the fetus and newborn, especially in our social context. PABC patients typically present with breast lumps and enlargement on examination, and masses on imaging. Reduction of breast glandular tissue volume is rare in breast cancer, and few case reports of breast cancer with breast shrinkage are reported in the literature, which were not pregnancy-associated. We are presenting a series of three cases of PABC where we observed ipsilateral breast shrinkage with reduction of fibroglandular tissue as unusual radiological findings in these patients.

Asian Journal of OncologyVol. 11
Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
Openalex Percentile: Top 45%
Cancer Risks and Factors
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